Melittin derived peptide-drug conjugate, M-DM1, inhibits tumor progression and induces effector cell infiltration in melanoma by targeting M2 tumor-associated macrophages

BackgroundMelanoma has the highest mortality rate among all the types of skin cancer.In melanoma, M2-like tumor-associated macrophages (TAMs) are associated with the invasiveness of tumor cells and a poor prognosis.Hence, the depletion or reduction of M2-TAMs is a therapeutic strategy for the inhibition of tumor progression.The aim of this study wa

read more

The qualitative research proposal

Qualitative research in the health sciences has had to overcome many prejudices and a number of misunderstandings, but today qualitative research is as acceptable as quantitative research designs and is widely funded and published.Writing the proposal of a qualitative study, however, can be a challenging feat, due to the emergent nature of the qual

read more

Asymptomatic Bacteriuria in Pregnant Women

Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0

read more